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Tartagni Marco Position Faculty -> Associate Professor Location Arces - Lyras Phone Phone: 0547339233 Mobile: 3204365434 Mail This e-mail address is being protected from spam bots, you need JavaScript enabled to view it     Publications M. Rossi, F. Thei and M. Tartagni, "A Parallel Sensing Technique for Automatic Bilayer Lipid Membrane Arrays Monitoring", 2012 Mar Sensors & Transducers Journal ISSN 1726-5479 14-1 463 F. Thei, M. Rossi, M. Bennati, M. Crescentini, M. Tartagni, " An Automatic Offset Correction Platform for High-Throughput Ion-Channel Electrophysiology ", 2010 EUROSENSORS XXIV Linz 487 M. Rossi, F. Thei, H. Morgan, M. Tartagni, "A Disposable Microfluidic Array Platform for Automatic Ion Channel Recording", 2010 MicroTAS Groningen 487 F. Thei, M. Bennati, M. Rossi, M. Crescentini, M. Tartagni, "Concurrent Acquisition Approach for High Resolution Sensor Arrays", 2010 SENSORDEVICES 2010 Venice An increasing amount of sensor applications require multiple data acquisition with high resolution in truly parallel fashion. This requirement is particularly useful in the field of Nanotechnology where concurrent acquisition is required to understand the correlation between weak stochastic events. In this paper, we will propose a sensor array readout approach where synchronous sigma-delta converters are interfacing each sensing point and whose outputs are concurrently downsampled by dedicated hardware for decimation processing. The approach shows the following advantages: on the one hand the sigma-delta conversion ensures high resolution and linearity (>12 bits), on the other, the 1-bit output allows easier routing access to the array. The approach is particularly useful in the presence of very low signals where direct raster-mode switching access to the array would compromise the signal-to-noise ratio of the readout process. As a proof of this concept, the approach is applied to an array of lipid bilayer membranes (BLMs) permitting to acquire and display single molecule event data by means of a PC-based graphical user interface (GUI). 487 F. Thei, M. Rossi, M. Bennati, M. Crescentini, F. Lodesani, H. Morgan, M. Tartagni, "Parallel Recording of Single Ion Channels: A Heterogeneous System Approach", 2010 May IEEE Transaction on Nanotechnology 1536-125X 9 3 295-302 487 M. Crescentini, M. Rossi, M. Bennati, F. Thei, A. Baschirotto, M. Tartagni, "A Nanosensor Interface based on Delta-Sigma arrays", 2009 Jun 3rd IEEE International Workshop on Advances in Sensors and Interfaces, IWASI Trani An emerging area of biosensors is based on the use of structures provided by recent advances of Nanotechnology such as nanowires, nanotubes and nanopores provided by recent advances of Nanotechnology. More specificallyAmong them, the integrated useintegration of natural nanopores of such as ion channels and with electronics is a promising approach to develop rapid, sensitive and reliable biosensors able to detect low concentration of target molecules or DNA sequencing. This paper presents a compact and low-cost system able to readout, process and record current in the pA range, provideds by biological or synthetic nanopores. The approach is based on the idea that by processing the outputs of a large amount of single-molecule nanosensors is the key point towould result in a significant increase of resolution and signal-to-noise ratio. The approach consists of an electronic interface able to detect current-based array of nanosensors, where the management of very large amount of data is critical for the readout process. As working example, we acquired the single molecule signals derived from non-covalent bindings between single α-hemolysin pores, embedded into an artificial lipid bilayer, and β-cyclodextrin molecules. The system embeds the electronic readout with the microfluidic where is placed the nanosensor array. The electronic interface is a 0.5mm2 current amplifier based on an array of ΣΔ converters. Then the high rate data streams are processed and downsampled by a DSP that communicates with a PC via a USB interface for data processing and storage. 487 M. Bennati, F. Thei, M. Rossi, M. Crescentini, G. D'Avino, A. Baschirotto, M. Tartagni, "A Sub-pA Delta-Sigma Current Amplifier for Single Molecule Nanosensors", 2009 Feb International Solid State Circuit Conference, ISSCC 2009 52 348--350 San Francisco A current readout front-end for nanosensors based on a delta-sigma converter approach features an input equivalent noise, below 5fA/sqrt(Hz) enabling the detection of current signals in the pA range in the kHz bandwidth. The device operates for detecting ion channel modulations caused by single molecule interactions. In a 0.35µm 2P4M technology, the devices occupies 0.5 mm2 and consumes lower than 23mW. 487 S. Furini,C. Domene, M. Rossi, M. Tartagni, S. Cavalcanti, "Model-Based Prediction of the a-Hemolysin Structure in the Hexameric State", 2008 Biophysical Journal 95(5) 2265-2274 463 H.V.B. Achar, M. Rossi, S. Cavalcanti, E. Giordano, E. Sangiorgi, M. Tartagni, "Single Particle Counter Using Nanopores: Multiphysics Simulations and Experiments", 2008 Sep IASTED International Conference on Nanotechnology and Applications (NANA) 95(5) 37-40 Crete 463 M. Rossi, M. Bennati, F. Lodesani, S. Branchetti, M. Tartagni, "A Compact System for Ion Channel Recording", 2007 IEEE Sensors 2007 Conference Atlanta 156 M. Bennati, F. Lodesani, M. Crescentini, A. Mariani, M. Tartagni, "A Delta-Sigma Approach for Ion Channel Based Biosensor Arrays", 2007 Transducers 2007 Lione 156 M. Sergio, N. Manaresi, M. Tartagni, R. Canegallo, R. Guerrieri, "On road tire deformation measurement system using a capacitive-resistive sensor", 2007 Smart Materials and Structures, In Press, Accepted for publication. F. Lodesani, M. Bennati, C. Fiegna, M. Tartagni, "Quantitative Detection by Single Ion Channel Event Statistics: an ", 2007 NSTI Nanotech 2007 Santa Clara 156 S. Callegari, G. Merendino, A. Golfarelli, M. Zagnoni, M. Tartagni, "Applicability of Field Programmable Analog Arrays to Capacitive Sensing in the Sub-pF Range", 2006 Analog Integrated Circuits and Signal Processing, vol. 47, pp. 39-51, Apr. 2006 A.B. Fuchs, A. Romani, D. Freida, G. Medoro, M. Abonnec, L. Altomare, I. Chartier, D. Guergour, C. Villiers, P.N. Marche, M. Tartagni, R. Guerrieri, F. Chatelain, N. Manaresi, "Electronic sorting and recovery of single live cells from microlitre sized samples.", 2006 Lab on a chip, (2006) Jan, 6(1): 121-6 S. Callegari, M. Zagnoni, A. Golfarelli, M. Tartagni, A. Talamelli, P. Proli, A. Rossetti, "Experiments on aircraft flight parameter detection by on-skin sensors", 2006 Sensors and Actuators A, 130-131 (2006) pp. 155-165 P. Vulto, G. Medoro, L. Altomare, G. A. Urban, M. Tartagni, R. Guerrieri, N. Manaresi, "Selective sample recovery of DEP-separated cells and particles by phaseguide-controlled laminar flow", 2006 Journal Of Micromechanics And Microengineering 16 (2006) pp. 1847-1853 M. Zagnoni, A. Golfarelli, P. Proli, S. Callegari, A. Talamelli, E. Sangiorgi, M. Tartagni, "A Non Invasive Capacitive Sensor Strip for Aerodynamics Pressure Measurement", 2005 Sensors and Actuators A - Physical, 123124 240-248 M. Zagnoni, A. Rossetti, P. Proli, A. Golfarelli, S. Callegari, A. Talamelli, E. Sangiorgi, M. Tartagni, "A Thin Film Strip for Aerodynamic Body Pressure Profile Monitoring ", 2005 Digests of Technical Papers. Transducers '05, pp. 499-502, Seoul, 2005 S. Callegari, A. Golfarelli, M. Zagnoni, M. Tartagni, A. Talamelli, P. Proli, "Experiments on aircraft flight parameter detection by on skin sensors", 2005 Eurosensors XIX, Barcellona, 2005 S. Callegari, M. Zagnoni, A. Golfarelli, M. Tartagni, A. Talamelli, V. Rossi, "Flight attitude detection by measurements made on the aircraft skin using redundant strip pressure sensors", 2005 Atti del XVIII Congresso Nazionale AIDAA (Associazione Italiana di Aeronautica e Astronautica), DGMP srl, VOLTERRA (PI), 2005 S. Callegari, A. Golfarelli, M. Zagnoni, M. Tartagni, "Novel Measurement Method for AirData System Based on Strip Sensors: Experimental Results", 2005 Proceedings of IEEE Sensors 2005, IEEE Press, Irvine (CA), 2005 G. Merendino, S. Callegari, A. Golfarelli, M. Zagnoni, M. Tartagni, "Signal conditioning for capacitive sensors with Field Programmable Analog Arrays", 2005 ISSCS 2005 International Symposium on Signals, Circuits and Systems Proceedings, pp. 139-142, IEEE Press, Iasi, 2005 M. Sergio, N. Manaresi, M. Nicolini, D. Gennaretti, M. Tartagni, R. Guerrieri, "A Textile Based Capacitive Pressure Sensor", 2004 Sensor Letters, Vol. 2, No. 2, June, 2004, pp. 153-60 M. Jenkner, M. Tartagni, A. Hierlemann, R. Thewes, "Cell-based CMOS sensor and actuator arrays", 2004 IEEE Journal of Solid State Circuits, vol. 39, n. 12,pp. 2431 - 2437, 2004 M. Zagnoni, A. Golfarelli, P. Proli, E. Sangiorgi, M. Tartagni, "Cereal Grain Sorting by Impedance Spectroscopy Sensing", 2004 Proceeding of AISEM, Ferrara, February 8-11, 2004 M. Zagnoni, A. Golfarelli, P. Proli, E. Sangiorgi, M. Tartagni, "Using Impedance Sensing for Sorting Cereal Grains", 2004 proceedings of Eurosensor, Rome, 2004, pp. P1-83. M. Sergio, N. Manaresi, M. Tartagni, R. Canegallo, R. Guerrieri, "A Dynamically Reconfigurable Monolithic CMOS Pressure Sensor for Smart Fabric", 2003 IEEE Journal of Solid-State Circuits, Vol. 38 No 6 , pp. 966-975, June 2003. M. Tartagni, L. Altomare, R. Guerrieri, A. Fuchs, N. Manaresi, G. Medoro, R. Thewes, "Microelectronic Chips for Molecular and Cell Biology", 2003 Sensor Update, Volume 13, Issue 1 (Dec. 2003), pp. 155-200 M. Sergio, N. Manaresi, M. Tartagni, R. Canegallo, R. Guerrieri, "On road tire deformation measurement system using a capacitive-resistive sensor", 2003 22-24 Octobe presented at IEEE SENSORS 2003, Proc.IEEE Vol. 2 1059-1063 M. Sergio, N. Manaresi, M. Tartagni, R. Canegallo, R. Guerrieri, "A Mixed Signal Distributed Architecture for Wide-Area Pressure Sensor", 2002 presented at EUROSENSORS XVI, September, 2002. M. Sergio, N. Manaresi, M. Tartagni, R. Canegallo, R. Guerrieri, "A system-on-chip for pressure sensitive fabric", 2002 presented at AISEM 2002, February, 2002. M. Sergio, N. Manaresi, M. Tartagni, R. Canegallo, R. Guerrieri, "A textile based capacitive pressure sensor", 2002 presented at IEEE SENSORS 2002, 12-14 June 2002 Vol. 2 1625-1630 M. Sergio, N. Manaresi, M. Tartagni, R. Canegallo, R. Guerrieri, "A system-on-chip for pressure sensitive fabric", 2001 presented at the IEEE CICC, 6-9 May 2001, pp. 413-416.